Translational and Interventional Immunology (TI)

Characterization of Immune Responses

Immune Interventions

Late-breaking: Translational and Interventional Immunology

(701) Carbonic anhydrase 1 is a potent therapeutic target for mucosal and connective tissue mast cells.

(702) Senolytic Activities of TLR Agonist Stimulated Mesenchymal Stem Cell Secretome Based Cosmetic GlowSelle™

(703) Reverse Epitope Discovery of Asparaginase-Specific TCRs and Their Target Epitopes

(704) TLR2 sensing of the SARS-CoV-2 envelope protein drives NLRP3-dependent pyroptosis in post-COVID-19 systemic lupus erythematosus

(705) A systematic evaluation of T lymphocytes and metabolic parameters in childhood obesity: new therapeutic targets for the disease?

(706) Characterizing Immune Cell Sexual Dimorphism in Intracranial Aneurysm via Rat IA Model and Spatial Transcriptomics

(707) Advanced Cytometry Techniques for Immune-Based Therapy Analysis

(709) Frailty-Associated Immune Aging Signatures characterized by SASP and T Cell Effector Function Profiling

(710) Human Microbiota-Driven Mouse Model Improves Drug Metabolism Prediction

(711) Glutamine-Dependent Biosynthetic Pathways Fuel Autoreactive T and B Cells in Foxp3 Deficiency-mediated Disease

(712) Multimodal Interrogation of Autoimmune Disease Patients Reveals Highly Diverse Biomarker Signatures

(713) ST2 enforces a ‘repair-ready’ Treg phenotype that homes to and ameliorates neuroinflammation.

(714) Immune Regulatory Markers in Post-Acute Sequelae of COVID-19: A Clinical Case Report

(715) Circulating Monocytes are Associated with Centralized Pain in Patients with Rheumatoid Arthritis

(716) BKT300: A novel small molecule with strong anti-inflammatory and immune regulating activity

(720) Status of Current Clinical Trials on Therapy for Hereditary Angioedema

(721) Programmable Panels: A Web-Based Design Studio to Accelerate Custom Cytometry Panel Development for Clinical Immune Profiling

(722) High Dimensional Profiling of T cells in ME/CFS Uncovers Sex Specific Dysregulation

(725) Pregnancy-Associated Immune Features in COVID-19 Link Fetal Protection to Heightened Maternal Viral Risk

(726) Development of in vitro models to study CD137 agonist antibody mediated hepatotoxicity

(727) Identification of ICOS/ICOSL co-expression in Sézary syndrome and their therapeutic targeting.

(728) Time to initial infusion therapy in Primary Immunodeficiency: A community-based retrospective analysis

(729) Collateral Immune Cell Signaling Compromises the Efficacy of T-cell Engaging Therapies for Cardiac Fibrosis

(737) Curcumin and Berberine as Potential Therapeutic Agents Targeting ACSL4-Mediated Ferroptosis in Glioblastoma

(738) Integrative Multi-Omics Profiling Identifies Candidate Biomarkers in Triple-Negative Breast Cancer

(739) Xenotransfusion of Triple-Knockout Porcine Red Blood Cells: Effects of hCD55/hCD39 Expression and Anti-CD154 Therapy in Non-Human Primates

(740) Embryonic Stem Cell–Derived Signals as Potential Modulators of Prostate Tumor Cell Growth

(741) Enhancement of Regenerative Activity Subsequent to SenoVax(TM) Senolytic Immunotherapy

(742) Cytokine Programming Combined with 4-1BB Enrichment Enhances Ovarian TIL Expansion and Function

(743) Modular engineering of Tregs for the treatment of inflammatory and autoimmune diseases

(744) The immunomodulatory potential of a medicinal plant-derived exosome-like nanovesicles and their applications in inflammatory skin disorders

(745) Investigating the Role of 7-Ketocholesterol in Alleviating Inflammatory Bowel Disease (IBD) using an Acute Mouse Model of Chemically Induced IBD

(746) Optimized arenavirus vectors with tumor-tropic mutations as new class of amplificators of anti-tumoral T cell responses

(747) Personalized Endocrine Disrupting Chemical Reduction Improves Inflammation and Metabolic Health In Reproductive-Aged Adults

(748) Unique immunization strategies elicited antibodies in mice binding to the specific GPCR target on live cell surface across a panel of Class A GPCRs

(749) Decoupling Drug Exposure, Binding ADA, and Functional Neutralization in Anti–PD-L1 Therapy Using Orthogonal ELISA Immunogenicity Assessment

(750) Characterizing MTRNR2L1 as a Novel Pseudogene Associated with Glioblastoma Cell Survival

(751) Evaluating the Immune Response to the Artificial Oxygen Carrier OxyVita®

(752) CX-01 Improves Survival and Attenuates Organ Failure in a Rat Polytrauma Model

(753) The Neutrophil Elastase Inhibitor Sivelestat Improves Organ Function And Reduce Mortality In A Rat Polytrauma Model

(754) TREM-1-mediated modulation of innate immune response in acute and chronic inflammation: Effect of treatment timing and cell specificity on outcome

(755) Targeting Interferon-Primed Neutrophils to Halt Microvascular Inflammation in HFpEF: A Novel Path to Immune-Guided Cardiac Intervention

(756) Evaluating Bruton Tyrosine Kinase Inhibition in T-Cell Leukemia and Lymphoma Models

(757) Investigating the Role of A2A Signaling in Caffeine-Induced EL4 T-Cell Lymphoma Growth

(758) Post COVID-19 Rise in Postural Orthostatic Tachycardia Syndrome and Antibody Deficiency: Exploring Immunoglobulin Therapy for Symptom Management

(760) Unmasking a Rare Infectious Complication of Th2 Pathway Inhibition: A Case of Iliopsoas Abscess Post-Dupilumab.