Technological Innovations in Immunology (TECH)

Late-breaking: Technological Innovations in Immunology

Technological Innovations in Immunology I

Technological Innovations in Immunology II

(531) 3D Assessment of Immunomodulatory Effects of Cytokine-treated Mesenchymal Stromal Cells Using AI-Based Organ and Tissue Detection Methods

(532) ELISA-Based Neutralizing Antibody (NAb) Detection as a Fit-for-Purpose Alternative to Cell-Based Assays for Biotherapeutic Immunogenicity Assessment

(533) Target-specific monoclonal antibodies detect the GPCRs PAR1 or DRD2 expressed on live cell surfaces by Flow Cytometry

(534) Engineered anti-inflammatory peptides for modulation of Toll-like receptor-mediated inflammation

(535) Simultaneous Detection of Transcription Factors and RNA Using TotalSeq™ Antibodies with 10x Genomics Chromium Single Cell Flex Gene Expression

(536) Expanding Antibody Labeling Options: TrailBlazer™ Tag and StarBright™ Dye Label Kits

(537) Enhancing Flow Cytometry Multiplexing Panels with New StarBright™ Spectral Dyes

(538) Xynapse-T – an antigen-specific scaffold for functional stimulation and expansion of T-cells

(539) Breaking The Detection Barrier With SMC® 2-Plex Immunoassays Revealing Hidden Cytokine Signatures in Autoimmune Diseases

(540) A Scoring System Using Visual and Artificial Intelligence Analysis Quantifies HEp-2 Cell Slide Quality for Optimal Antinuclear Antibody Testing

(541) STEMprep™ Automated Tissue Dissociation System: Maximize Cell Viability and Yield

(542) Human NK Cell Enrichment and Expansion Using Defined GMP Reagents: Functional and Phenotypic Outcomes

(543) Validated high throughput microneutralization assay for anti-AAV2 neutralizing antibodies (NAbs) in clinical trials in support of gene therapy

(544) Mechanoporation-based Intracellular Delivery of Functional Molecules for Primary Immune Cell Engineering

(545) Lyophilized Listeria monocytogenes vaccines for storage at non-ultra-low temperatures and cancer therapy

(546) Developing a Label-Free High-Throughput Flow Assay by Imaging Cytometry on the Attune CytPix

(547) Apotracker™ Peptides Facilitate Calcium-Independent Phosphatidylserine Targeting for Extracellular Vesicle Isolation and Analysis

(548) Targeting the Idiotype: Nanobody-Based PET Imaging of Antigen-Specific T Cells in Experimental Autoimmune Encephalomyelitis

(549) Mapping the chromatin landscape of the mouse immune system with low-input automated CUT&RUN

(550) Uncovering novel regulators of immune response in rhesus macaque single-cell RNA-seq data

(551) A Complete Multiomic Solution: WTA NEXT Powers Deep Immune Profiling Across mRNA, Surface Proteins, and VDJ in One Assay

(552) Rapid Bioluminescent Monitoring of Granzyme B Production and Activity

(553) High-Throughput Immunomodulator Screening Reveals Subtype-Specific Responses in Low-Abundance Immune Cell Populations Using Scalable scRNA-seq

(554) Hybrid Cytometry: automated live-cell tracking with a final snapshot of fixed-cell phenotyping to study immune-synapse dynamics

(565) Decoding the Antibody Reactome at Scale with Novel Antigen Display Technology to Decipher Immune History

(566) Leveraging Advances In Long-Read Sequencing to Improve Analysis of Host Immune Responses

(567) Spatial proximity sequencing maps developmental dynamics in the Germinal Center

(568) Nanobody-based Tools for in-depth Research of Immuno-Oncology Targets

(569) Immune-Stromal Co-culture System to Interrogate Cytokine Responses in Rheumatoid Arthritis

(571) Unraveling genomic regulatory complexity by adding chromatin accessibility to the long-read sequencing toolkit

(572) From Epitope to Therapy – Selecting the Right TCR

(573) A Novel Flow Cytometry Array for High Throughput Detection of SARS-CoV-2 Antibodies

(574) Streamlined and cost-effective 96-well plate NGS assay for single-cell immune receptor chain pairing and T/B cell immunophenotyping

(575) A novel, rapid, and simple Enzyme-linked immunoassay for C-reactive protein, A cardiovascular marker

(576) Development of strategies to visualize spatially resolved, stimulated cytokine secretion in live tissue slices

(577) Flow Cytometric Evaluation of SYTO 9 Green Staining in Empty and Loaded Lipid Nanoparticles Using the CytoFLEX nano Flow Cytometer

(578) Manufacturing CAR-T Cells in a Closed-System, End-to-End Manufacturing Workflow Enhances CAR-T Cell Function

(579) Enhanced Neutrophil Depletion in a Lung Tumor Model Using Recombinant IgG2c Anti-Ly6G [1A8] Antibody

(580) Automated C-FREE™ Workflow for Reproducible Memory T-cell and NK-cell Immunophenotyping

(581) Ultra-Sensitive Cytokine Quantification Using Binding Oligo Ladder Detection: A Universal Signal-Amplification Strategy for Standard Immunoassays

(582) Quantitative Analysis of a Novel Systems-predicted Neutralizing Antibody Titer Assay

(583) Novel mouse models for immunology research

(584) High-Throughput Multiplexed Single-Cell Analysis Using Protein Barcoding with Pacific Blue and DyLight800

(585) Innovative MESF Standards for Accurate Quantification of Biological Nanoparticles in Flow Cytometry

(586) Pulse Qualification Technology

(587) Staining and Characterizing Extracellular Vesicles from Platelet-Poor Plasma Using the CytoFLEX nano Flow Cytometer

(589) Evaluation of Vesiculab Vesi-Ref CD63- mNeonGreen (mNG) Extracellular Vesicles (EV) Reference Standard on the CytoFLEX nano Flow Cytometer

(590) A Whole Blood Fixation Strategy for Scalable Paired Single Cell Whole Transcriptome and Immune Receptor Profiling

(591) A novel silicon-based intracellular delivery platform enables multiplexed delivery across cell types and cell states

(592) Decoding Single-Cell Protein Interactomes with the Proximity Network Assay

(593) Assessment and development of computational strategies for assembling the human FCGR2/3 locus using Nanopore long-read sequencing data

(595) Buildable linkers: Site-Specific Antibody-Drug Conjugates with Well-Defined Payloads.

(596) Enabling single-cell multiomics to unravel complex data from human lung cancer tissue preserved in a novel long-term storage buffer

(597) Single-Cell Multimodal Functional Glycan Profiling Identifies Novel T Cell Immunomodulatory Glycan Signatures

(598) Cataloging Epitope Data: A glimpse into the manual curation efforts of the IEDB team in 2026

(599) Preserving neutrophils in single cell sequencing – our experience with a multi-center cohort

(600) Unravelling mitochondrial dynamics in T cells using high-speed image-enabled flow cytometry