Innate Immune Responses and Host Defense: Cellular Mechanisms (INC)

Innate Immune Responses and Host Defense: Cellular Mechanisms II

Innate Immune Responses and Host Defense: Cellular Mechanisms III

Innate Immune Responses and Host Defense: Cellular Mechanisms I

Late-breaking: Innate Immune Responses and Host Defense: Cellular Mechanisms

(400) The mTOR pathway in pristane -induced lupus models

(402) Therapeutic Evaluation of a C3-Targeting Small Nucleic Acid Drug in a Spontaneous Humanized C3 Glomerulopathy Mouse Model

(403) Epithelial tissue factor drives pneumococcus-mediated necrosuppurative pneumonia

(404) The C-type lectin receptor Mincle is functionally expressed by murine bone cells and can mediate inflammatory responses to Staphylococcus aureus.

(405) Mechanisms Underlying Increased Susceptibility and Severity of Bacterial Keratitis in Diabetic Mice

(406) IL-17A⁺ γδ T Cells Are Compromised by ICU-Associated Sleep Fragmentation, Increasing Pneumonia Susceptibility

(407) Investigating the Role of IL-27 During Gram-Positive Neonatal Sepsis

(408) Macrophage–NK Cell Crosstalk via cGAS–STING Signaling Induces IFN-γ Responses Critical for Early Control of Borrelia burgdorferi Infection

(409) Defining Macrophage Polarization Signatures via Bioactive Recombinant Proteins and LEGENDplex™ profiling

(410) Macrophage Anti-bacterial Activity is Controlled by Adenylate Kinase 4-Mediated Mitochondrial DNA Synthesis

(411) Investigation of LOX-1 as an Immunometabolic Regulator During Lung Infection

(412) Acute versus Sustained Type I Interferon Signaling Drives Divergent Outcomes in Post‑Influenza Staphylococcus aureus Pneumonia

(413) Elevated TGF-β/IL-10 in platelet-monocyte complexes exacerbates atherosclerosis in people with HIV

(414) Inflammatory Monocyte Responses and Endothelial Stress in Young Adult E-Cigarette Users

(415) Ketogenic diet-mediated immunometabolic regulation improves airway clearance of Klebsiella pneumoniae

(416) Antibody Recruiting Small Molecules as Immune Probes

(417) Stress-adapted Immunity: The Integrated Stress Response as a Driver of S. aureus Biofilm Persistence

(418) Acute Fasting Suppresses Neutrophil Metabolism and Effector Function

(419) Role of NK cell clock in influenza infection

(420) Iron overload induces intestinal macrophage dysfunction and promotes enteric infection in hemochromatosis

(421) IDO-dependent metabolic reprogramming promotes K. pneumoniae airway infection

(422) Investigating the antibacterial and pro-coagulant activity of neutrophil-derived extracellular vesicles induced by phagocytosis of S. aureus.

(422) Prior RSV Infection Enhances Alveolar Macrophage Function and Protects Against Secondary S. pneumoniae Infection

(423) Host Peroxisome Proliferator-Activated Receptor Alpha is Essential for Coxiella burnetii Intracellular Survival and Prostaglandin E2 Production

(424) Bisphenol-A (BPA) exposure dysregulates wound healing in larval zebrafish

(424) Dual Immunomodulatory Roles of MARCKS in Proinflammatory and Type I Interferon Signaling in Macrophages

(425) Regulation of Neutrophil Heterogeneity and Effector Functions by the NLRP3 Inflammasome in Sepsis

(426) Cell Intrinsic Programmed Death-Ligand 1 (PD-L1) Signaling Limits Low Affinity T cell Responses during Acute Infection with Listeria Monocytogenes

(429) Immunomodulatory Effects of Atrazine in Human A549 Lung Epithelial Cells

(431) Pro-Inflammatory Response of Human Monocyte-Derived Dendritic Cells to Bacterial Biofilms

(433) TLR11/12-mediated regulation of optimal myelopoiesis during Toxoplasma gondii infection

(434) Investigating the role of the innate immune system in releasing neutrophil extracellular traps (NETs) in response to acute Toxoplasma gondii infection

(437) Eosinophil–macrophage crosstalk controls obesity-associated adipose inflammation and is stabilized by RELMα in a sex-dependent manner

(438) Investigating the role of Galectin-3 in a model of lung granuloma formation

(439) Elucidating the Function of Redox-Signaling Mechanisms Underlying Trained Immunity in Alveolar Macrophages

(440) CD14 directs Fas-mediated apoptosis in dendritic cells to restrain neutrophil-driven psoriatic inflammation

(440) Role of polyunsaturated fatty acids in regulating innate immune antiviral and inflammatory response during respiratory syncytial virus infection

(441) Investigating the Role of Mast Cell Condensates in Regulating Macrophage Phenotype and Dynamics in Tissue Repair

(441) Resistin-Like Molecules Modulate Lung Immunity during Influenza

(442) Neuroinflammatory Responses in Glial-Immune Interactions to Francisella tularensis in the Central Nervous System microenvironment

(443) Distinct subsets of tissue-recirculating NK cells revealed by single cell transcriptomic analysis of lymph- and blood-borne cells in sheep

(444) The Indigestible Burden of Microplastics Drives Bioenergetic Dysfunction in Macrophages

(445) Macrophage infiltration leads to Mast Cells activation differentiated from MCPs of PAT exacerbating Cardiac Fibrosis after Myocardial Infarction

(446) ScRNA-seq Analysis of Olfactory Epithelium in Chronic Rhinosinusitis with Nasal Polyps

(447) Neutrophil Formyl Peptide Receptor-1 Activation Triggers Endogenous Opioid Release for Local, Non-addictive Analgesia

(448) Gli3 Regulates PD-L1 Expression in Macrophages and Alters Maturation and Cytokine Profiles in Plasmacytoid Dendritic Cells

(449) CD15+ Myeloid Cells from Patients with Disseminated Coccidioidomycosis Inhibit CD4+ T Cell Proliferation

(450) Spatiotemporal Regulation of RIG-I-Like Receptor Signaling by Endosomes

(450) Ultra-small Saccharibacteria modulate immunoactivation through type IV pili and TLR2

(451) A humanized mouse model to study immune complex processing and clearance

(452) MicroRNA-1246 regulates macrophage lipid metabolism and is involved in resistance to human Mycobacterium tuberculosis infection

(453) Endoplasmic reticulum stress as a determinant of Mycobacterium tuberculosis survival in alveolar macrophages

(454) Platelet Origin TGFβ Mediates Immunosuppressive Effects in Monocyte Derived Dendritic Cells in People Living With HIV

(455) Exploring the role of complement in extracellular vesicle production: Insights into host-pathogen interactions

(456) Siglec15 and Siglec14 are new immune check point receptors during Mycobacterium tuberculosis infection of human macrophages.

(458) 4F2hc mediated amino acid transport drives metabolic reprogramming and orchestrate NK cell effector functions

(459) High-dimensional flow cytometry analysis reveals temporal dynamics of lung macrophages during Mycobacterium tuberculosis infection

(460) Innate immune response to Vibrio cholerae in infant mouse model

(461) Macrophage regulation of inflammation in type 2 diabetes

(462) Chronic Inflammation Induces a Molecular and Functional State Divergent from Physiological Aging in Hematopoietic Stem Cells

(464) CD137 and IFN-γ signaling in mature cDC2Bs play a central role in the regulatory feedback mechanism for alloimmune responses

(466) Fh15 Modulates Human Neutrophil Activation and Reduces NETosis

(467) Genetic Depletion of Tumor-cell Derived Complement Factor H Suppresses Glioblastoma Development

(468) UCD200/206 scleroderma-prone chickens show aberrant innate immune function

(469) IL-33 Expands M2 Macrophages population and Restrains Inflammatory Monocyte Recruitment During Clostridioides difficile Infection

(470) Investigating Inflammasome Responses to Pathogenic Fungi

(471) Constant engagement of a natural killer (NK) cell activation receptor with self-MHC-I renders hyporesponsive NK cells