Viral Immunology (VIR)

Late-breaking: Viral Immunology

Viral Immunology I

Viral Immunology II

(868) Loss of HIV-1-specific neutralizing antibodies via Δ42PD-1 positive B cells

(869) CD39 restrains ATP–P2X7-driven inflammatory cell death and neuroinflammation during neonatal Zika virus infection

(870) Viral modulation of antigen presentation: influenza A viral protein PA-X disrupts MHC I during infection

(871) Type I interferons prevent cell death and liver immunopathology in Mouse Hepatitis Virus infected mice

(872) A novel LNP/mRNA-based STING immunotherapy approach for chronic HBV infection

(873) Serpin B1 prevents severe pulmonary influenza through specific effects on T cells and NK cells

(874) Persistent expression of myeloid lineage markers in resident and circulating T cells induced by SARS-CoV-2 infection

(875) STAT1 dependent local IFN response in axons impairs retrograde alpha herpesvirus capsid transport

(876) Evaluating memory B cell cross-reactivity between ancestral and future SARS-CoV-2 variants – evidence for original antigenic sin

(876) Impact of innate immune training on lung tissue resident memory formation following RSV infection

(877) A neonatal bias towards CX3CR1++ memory CD8+ T cells is associated with impaired control of Cytomegalovirus in early life

(877) Mitigating Placental Inflammation is Necessary for Improved Fetal Outcomes following Maternal H1N1 Infection

(878) Characterization of Non-Neutralizing Antibody Responses in a Dengue Virus-4 Human Challenge Model

(878) SARS-CoV-2 endoribonucleaseU and ORF6 work synergistically to antagonize innate immune signaling

(879) Characterization of Anti-influenza B Hemagglutinin Antibodies

(880) Defining pulmonary immune responses in microbially experienced mice.

(880) The effect of type I interferon on infection and the CD8 T cell response to Coxsackievirus B3

(881) Defining the Role of the RSV Small Hydrophobic Protein in Viral Pathogenesis

(882) Investigating the Susceptibility of Peripheral Immune Cells to Human Respiratory Syncytial Virus (RSV) Infection

(882) Presentation by Virally Infected Cells of Antigenic Proteins Utilized in Natural Killer Cell Antibody-Dependent Cell-mediated Cytotoxicity (ADCC)

(883) Investigation of immune mechanisms driving the pathogenesis of chronic chikungunya virus disease

(883) TLR4–Spike Interaction Mediates Metabolic Reprogramming in Human B Cells

(884) Impact of Epstein-Barr Virus LMP2A on Toll-Like Receptor 9 (TLR9) expression and function

(884) Spike-specific de novo CD8+ T cell clones exhibit robust effector phenotypes in the context of hybrid immunity

(885) Differentiation, programming, and (dys)functions of cytotoxic CD4 T cells in acute and chronic viral infection

(885) PD-1-mediated T cell dysfunction drives age-dependent susceptibility to La Crosse virus encephalitis in mice

(886) Identifying Macrophages as Peripheral Transporters of JC Polyomavirus

(886) The E3 Ligase RNF11 is a novel regulator of type I Interferon-independent antiviral defenses critical for restricting viral infection in macrophages

(887) Infection history shapes envelope-specific IgG repertoires with convergent neutralization from multiple lineages in secondary dengue

(887) Proximity Proteomics Identifies IFI16 as a Host Factor of Human Coronavirus Infection

(888) CXCL10 orchestrates immunopathogenic CD4+ effector recruitment in alphavirus arthritis

(888) Viral infection tunes B cell receptor copy number

(889) Characterization Of Usutu Virus Replication And Associated Immune Response In Vitro

(889) Neuregulin-1 Prevents RSV Induced Disruption of Human Airway Epithelium Polarity

(890) Elevated type I interferon levels during Influenza virus infection profoundly suppress pulmonary innate and adaptive immunity and exacerbate disease.

(890) Fever Temperatures Differentially Alter Ebola-Antibody Functionality Depending on Affinity Maturation

(891) Antibody-Mediated Entry Renders Non-Susceptible Macrophages Permissive to SARS-CoV-2 Replication

(891) Neutrophil Elastase Regulates both Innate and Adaptive Immunity in SARS-CoV-2-Infected Mice

(892) From Acute to Chronic SARS-CoV-2 Infection: Viral Persistence, T Cell Response, and the Essential Role of Regulatory T Cells

(892) Understanding long term consequences of respiratory viral infection

(893) Epithelial Toll-Like Receptor 9 Upregulation by Influenza Virus Impairs Pulmonary Antibacterial Immunity.

(893) The Role of Pathogen-Restricted Paracrine Protection by T cells in Controlling Viral Infection

(894) Covid19 Effects on V-ATPase Subunit Gene Expression in Ionocytes that Regulate Ion and pH Homeostasis in the Oral Cavity

(894) Paneth cell dysfunction regulates host response to SARS-CoV-2 infection

(895) Innate Immune Sensing of HIV Defective Provirus Transcripts Contributes to Chronic Inflammation

(895) Measurement of the Reduction of OC-43 Coronavirus Production by Natural Killer Cell Antibody-Dependent Cell-mediated Cytotoxicity (ADCC)

(896) Dengue-specific T cell immunity influenced by various levels of pre-existing immunity

(896) Vitamin D Supplementation Improves Human Natural Killer Cell Responses to JC Polyomavirus Infection

(897) CMKLR1 Regulates Microglial Activation and Migration During West Nile Virus Encephalitis

(897) Rapid IFNg production by CD8+ TRM slows viral propagation but is insufficient to directly mediate clearance following respiratory virus transmission

(898) Dissecting Zika Virus pathogenesis through maternal-fetal immune interactions and sex-based susceptibility

(898) Plasmacytoid dendritic cell discrete subpopulations with contrasting functions are elicited by CD4+ T cells infected or not by HIV-1 or HIV-2

(899) Differential B Cell Epitope Recognition in Closely Related Arbovirus Infections

(900) Ebola virus exploits host lncRNA LINC01740 to enhance ATF3 and suppress antiviral immune responses

(900) Impact of Thymus Removal in Altering CD8 T Cell Properties

(901) Cytokine training primes NK cells for enhanced antiviral activity against JC polyomavirus

(901) Single cell characterization of early innate immune responses induced by acute and chronic viral infections

(902) Dissecting the Endothelium–CD8 T Cell Crosstalk in Vascular Antiviral Immunity

(902) TCR affinity mediated T cell clonal type development

(903) Caspase-8 regulates cell death and inflammatory responses in complex respiratory infection

(903) Type 1 interferons (T1 IFNs) regulate cellular redox balance by suppressing the host antioxidant response during influenza A virus infection in vivo

(904) IgA Dengue Virus NS1 Immune Complexes Are Associated with In Vitro Neutrophil Activation

(904) SARS-CoV-2 vaccination protects against infection-induced autoantibody formation

(905) Gut Microbial Translocation may drive NK cell Reprogramming in Adolescents Living with Perinatally Acquired HIV

(906) Cytokine, plasmablast, and clinical biomarker profiles following monovalent dengue vaccination in individuals with distinct immune histories

(906) Investigation of the role of the cystic fibrosis transmembrane conductance regulator (CFTR) in SARS-CoV-2 pathogenesis

(907) Neutrophil Activation is Associated with Decreased Dengue Vaccine Replication in Human Recipients

(908) Mpox virus can suppress virus sensing and antiviral Responses in testicular cells: potential role of Sirtuins

(909) Neutrophils Display Limited Antiviral Activity Against HIV-1 Immune Complexes

(910) Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology

(911) Sex difference in viral reservoir and intestinal immune responses during simian HIV infection and antiretroviral therapy in rhesus macaques

(913) Persistent NK Cell Dysfunction May Be Linked to Gut Dysbiosis in HIV Despite Long-Term Antiretroviral Therapy (ART)