Lymphocyte Differentiation and Peripheral Maintenance (LYM)

Late-breaking: Lymphocyte Differentiation and Peripheral Maintenance

Lymphocyte Differentiation and Peripheral Maintenance I

Lymphocyte Differentiation and Peripheral Maintenance II

(445) IL2 signaling and Foxp1 expression maintain Treg identity in the absence of Foxp3

(446) Tissue resident NK cells establish residency via KLF2-independent pathways

(447) The CARD11-BCL10-MALT1 (CBM) Complex Regulates Nutrient Transport and mTORC1 Activation to Shape CD4+ T Cell Differentiation

(448) Human CD127⁺CD45RA⁺CCR7⁻CD8⁺ T cells represent an early-memory population governed by FOXP1

(449) Unbiased Multiparameter Analyses Reveal Mechanisms of Variable Restimulation-Induced Cell Death Sensitivity across Human T cell Populations.

(451) The Impact of Age-Associated Lymph Node Microenvironment Changes On Dendritic Cell:CD4+ T Cell Interactions During Germinal Center Initiation

(452) Tunable Immune Imprinting of Memory B Cells to SARS-CoV-2 Variants

(453) Whole Body Irradiation (WBI) impairs antigen-independent functions of memory CD8 T cells

(454) Intestine-Resident Memory T Cells Are Differentially Controlled by TGF-β

(455) The regulatory subunit ppp2r5a of protein phosphatase 2A selectively regulates spleen B-1 cell proliferation and accumulation

(456) Limited sustainability of regulatory T cell repertoire revealed by novel genetic switches

(457) The Influence of B-Cell Intrinsic IL-1β on the Long-Term Maintenance of Antibody Secreting Cells

(458) Overexpression of FGF21 in thymic stromal cells enhances T cell responses to viral infection and immune checkpoint inhibition efficacy during aging

(459) Unique Transcriptional and Functional Profiles of Neonatal Naïve CD4+ T Cells Expressing KLRG1

(460) The role of the T-cell receptor (TCR) in the generation of lung CD4+ tissue-resident memory T cells (TRM) following influenza infection

(461) Tissue-specific regulation of human secondary lymphoid organ responses: a systems approach

(462) Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection

(464) IL-1b-driven bystander proliferation of memory CD4 T cells partially depends on IL-2

(465) Modeling the Impact of Memory T Cell Activation on Lacrimal Gland Physiology

(466) Single-Cell Insights into Endothelial Cell Heterogeneity in the Thymus

(467) Natural variation in the activity of RUNX transcription factors pattern the development of effector and memory CD8 T cells

(469) Increased mTORC2 activity in naive T cells from older adults impairs asymmetric cell division

(470) Integrin αV-Mediated Spatially Restricted Activation of Autocrine TGF-β1 Programs Cytotoxic Tissue-Resident NK Cell Differentiation

(499) A unique epigenetic circuitry defines CD8 T cell stemness shared across chronic diseases

(500) Atomistic TCR-ligand interactions instruct memory T-cell differentiation

(502) Spatiotemporal and molecular factors determining T cell stemness and differentiation in autoimmune Type 1 Diabetes

(503) Facile Induction of Immune Tolerance by an Interleukin-2-TGF-β Surrogate Agonist

(505) Divergent roles for TLR7 and TLR9 in modulating the NFkB pathway in B cells

(506) Delineating the role of CXCR6 for the formation and maintenance of CD8+ tissue-resident memory T cells in the gut

(507) B Cells Under Pressure: How Losing Desmosterol Fuels Atherosclerosis

(508) Altered composition of peripheral immune subsets in Four Core Genotype mice

(509) Characterization of the Functional and Phenotypic Profile of a Naïve Conventional Innate-like Population of CD8+ T Cells in Neonatal Cord Blood

(510) Epigenetic reprogramming of terminal T cell differentiation via DNMT1 inhibition reverses terminal DNA methylation and enhances multipotency

(511) Aged lymph node stromal microenvironment as a driver of immune function decline

(512) Hallmarks of MHC-restricted T cell receptor repertoires

(513) Cellular ancestry determines plasma cell diversity

(514) Enhanced CD25 expression and IL-2/STAT5 signaling characterize β-galactosidase+ senescent and aged CD4+ T cells

(517) Characterization of the B1 Cell Repertoire in Sickle Cell Disease Pre- and Post-Pneumococcal Vaccination

(518) Collaboration among the common gamma chain cytokine family supports circulating and tissue-resident CD8+ T cell memory

(519) CD97-hi naive CD4 T cells are poised for Th1 responses and reflect inflammatory disease states

(520) Distinct Treg subsets in human peripheral blood are defined by unique transcriptomic signatures

(521) Harnessing the homeostatic proliferation capacity of memory CD8+ T cells to restore immune memory after radiation exposure

(522) Glucocorticoids redirect naïve T cells to the bone marrow for preservation in malnourished mice

(523) Effector competence is imprinted in thymic CD8+ T cells and regulated by PD-1 signaling

(524) Distinct epigenetic and transcriptional landscape of pathogenic CD44s-hiCD49dlo virtual memory CD8⁺ T cells in alopecia areata

(525) Discovery and delineation of human antibody-secreting cell subsets

(526) Aging Narrows Human B1-like Cell Repertoire and Impairs Defense Against Encapsulated Pathogens

(527) Diverse Microbial Exposure Enhances CD8+ T Cell Effector Memory Output and Function