Basic Autoimmunity (BA)

Basic Autoimmunity I

Basic Autoimmunity II

Late-breaking: Basic Autoimmunity

(100) Identification and characterization of a novel long non-coding RNA targeting DUSP22 in T cells of human systemic lupus erythematosus patients

(100) Loss of pressure induced constriction responses in cerebral vessels promotes injury and inflammation in a mouse model of systemic lupus erythematosus

(101) Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus

(101) Shared B cell receptor repertoire signatures across autoimmune diseases from integrated public datasets

(102) Human Treg Deep Phenotyping by Flow Cytometry: Advancing Immunosafety Assays in Autoimmune and Healthy Populations

(102) TLR9 and Type II IFN signaling in monocyte-derived macrophages orchestrate CD8 T cell activity in DNaseII deficiency-induced autoimmune hepatitis

(103) Distinct Effect of Type III Interferon on Trex1KO autoimmune model

(103) Progressive Development of Ectopic Lymphoid Structures as Mediators of Autoimmunity in a Sjögren’s Disease Mice Model

(104) Early Growth Response 2 (EGR2) Regulates Late B Cell Differentiation and Double-Negative T Cells in Lupus-Prone MRL/lpr Mice

(104) IP-10 Drives TCF1⁺ Stem-like CD8⁺ T Cell Depletion and Terminal Differentiation in Lupus Nephritis

(105) Glycolysis Dependence of Lupus Antigen-Specific B cells Linked to Mitochondrial Dysfunction and Age-associated B Cell Differentiation

(105) Phenotypic and Metabolic Signatures in Chronic Autoimmune Inflammation

(106) B cell intrinsic Ube2l3 is central to spontaneous germinal center formation and autoimmunity

(106) Increased CaMK4 Activity Drives Excessive CD8⁺ T-Cell Cytotoxicity in Systemic Lupus Erythematosus

(107) Evidence for the participation of selected gut microflora in epigenetic drug-mediated protection against autoimmune diabetes

(107) Machine learning-driven stratification of Immune disorders using serum cytokine autoantibody profiles detected by cell-based multiplex flow cytometry

(108) Divergent Immune Trajectories Influence Sex Bias in Aging Salivary Gland Autoimmunity

(108) Location-directed functions of CD11c in regulating B cell tolerance

(109) CD8 T cells require IFNg to induce disease in a murine model of Alopecia Areata

(109) Prior antigen experience influences the development of alopecia areata in C3H/HeJ mice

(110) A neuronal protein fine-tunes T cell immunity in the central nervous system

(110) Uncoupling autoreactive B cell receptor expression from autoimmune activation identifies early checkpoints in lupus

(111) Canonical Autophagy via Fip200 Shapes B Cell Homeostasis and Autoimmune Outcomes

(111) Smoking Tobacco Increases Extracellular Vesicles and Alters Their Cargo in the Blood of Multiple Sclerosis Patients.

(112) Bulk RNAseq of cardiac myosin-specific CD4 and CD8 T cells reveals distinct transcriptomic profiles between myocarditis-resistant and susceptible mice

(112) Sex-Specific Loss of SMS2-regulated Germinal Center B Cell Tolerance in Systemic Lupus Erythematosus

(113) Mapping REV-ERB𝛼’s Protein-Protein Interactions to Understand TH17 Cell Regulation and Inflammation

(114) Endosomal TLRs govern disease-stage specific B cell responses in Sjogren's disease

(114) Immunophenotypic Analysis of Alopecia Areata Progression in a C3H/HeJ Mouse Model

(115) Dual Reporter multiplexing enables simultaneous detection of IgG and IgM antibodies against autoantigens and pathogenic proteins in human samples

(115) Skin Gamma Delta T Cell Gene Expression Highlights Stress Response in Alopecia Areata

(116) B cells in Takayasu’s arteritis upregulate genes involved in RNA splicing, protein synthesis, and BCR signaling compared to healthy individuals

(116) Upregulation of Fatty Acid Metabolism in Activated Synovial CD4 T Cell Populations in Rheumatoid Arthritis.

(117) Human gut microbe, Parabacteroides distasonis, accelerates diabetes onset in mice without causing gut dysbiosis

(117) Losing Their Grip: Aging Weakens Treg TCR Catch Bonds Under Force

(118) Dietary Reversal of Dyslipidemia Ameliorates CD1b-Autoreactive T Cell-Mediated Skin Inflammation

(118) Lupus Nexus: A Registry, Biorepository, & Data Exchange Platform to Foster Global Collaborations, Accelerate Research, & Advance Precision Medicine

(119) Generation of Global and Liver-Specific Uricase Knockout Mice Modeling Hyperuricemia and Renal Pathology

(119) Negative charges in the surface of the SARS-CoV-2 spike protein promote autoantibody generation in hospitalized COVID-19 patients.

(120) Development of a sensitive assay for detection of pre-existing antibodies to de-risk biotherapeutic molecules for immunogenicity

(120) β-Catenin Stabilization Protects Against Alveolar Hemorrhage Through Amphiregulin and BATF-Mediated Regulatory T Cells

(121) Antigen-presenting cells in the initiation of autoimmune diabetes

(121) MHC-II polymorphisms regulate non-cognate negative selection of CD4 T cell orchestrators of type-1 diabetes

(122) Disruption of the Lung Microbiome Early in Life Protects Mice from Systemic Lupus Erythematosus

(122) Immunity to influenza B and cross-reactivity to Pandemrix/pH1N1 in narcolepsy

(123) Genetic variants of TYR and MC1R in biosynthesis of melanin and skin pigmentation are correlated with JDM and cSLE with photosensitive rash

(123) m6A RNA-binding Protein as a Novel Autoantigen in Rheumatoid Arthritis

(124) GARP expression on Tregs defines an antigen-specific highly suppressive population in demyelinating autoimmunity

(124) Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata

(125) Establishment of tissue-resident self-antigen-specific regulatory T cells protects the lung against recurrent injury

(125) Preliminary mapping of genes involved in the parent-into-F1 murine model of lupus nephritis

(126) Development of a sensitive and specific assay to detect the presence of immune complex in human serum

(126) SLE risk variants shapes IRF5 alternative promoter isoform usage in B cells

(127) CX3CR1 Signaling Drives Tertiary Lymphoid Structure Formation and Fertility Impairment Following Treg Depletion in the Epididymis

(127) Linking Genetic Risk to B Cell Dysfunction: Mechanisms of IL12A-mediated DN2 B cell Expansion in Lupus

(128) 14-3-3z Deficiency Drives B-Cell Dysregulation and Follicular Disorganization in Autoimmunity

(128) Structural Rewiring of TCR Docking by Protective HLA Alleles Drive Treg-Mediated Tolerance in Type 1 Diabetes

(129) Immune Modulation of T Cell Dysfunction in Tibia Fracture Model of Complex Regional Pain Syndrome

(129) Inflammatory arthritis irAE may represent a unique autoimmune disease primarily driven by T cells, but likely not autoantibodies

(131) Single cell profiling identifies effector CD8+ T cells and peripheral helper T cells as drivers of recurrent immunotherapy mediated arthritis

(132) Fibroblast PIEZO1 Promotes Autoimmune Valvular Carditis

(133) Plasma IgM inversely correlates with coronary artery AS risk

(134) Early-Life Overnutrition Reprograms Metabolism and Immunity to Promote Sex-Biased CNS Autoimmunity

(135) The Female Reproductive Tract is a Sex-Specific Site for Rheumatoid Arthritis Specific Biomarkers

(136) Decoding the role of CD4 T cells in driving autoimmune type 1 diabetes

(137) Antibodies in Guillain-Barré syndrome, the immune system’s double-edged sword.

(138) Characterization of Immune Cell Populations in Lupus Nephritis Using a SignalStar® Multiplex Immunohistochemistry Assay