Professor of Pathology and Immunology & Director of the School of Clinical Pathology and Clinical Biochemistry University of Modena - School of Medicine
High-parameter spectral cytometry maps immune architecture at single-cell resolution, measuring 30–40+ phenotypic, functional, and metabolic markers to capture full T cell, B cell, myeloid, and stromal diversity. This depth reveals previously unseen regulatory subsets and the cues shaping them. Computational models further infer signaling axes, activation paths, and shared cytokine, metabolic, and ligand–receptor networks that define cross-lineage immunoregulatory circuits.