Post-Doctoral Researcher Farber Lab Department of Microbiology and Immunology Columbia University Irving Medical Center
Extensive lymphocyte composition and numerical changes occur early in life as the immune system develops and encounters diverse microbiota. However, how these evolving immune populations influence one another during infection remains unclear. Using spectral flow cytometry, we profiled lymphocyte populations across development, revealing coordinated layering of B, T, and NK/ILC cells from birth to adulthood. Age shaped NK and T cell responses to CMV infection, generating distinct immune memory in infants and adults.
