Scalable ex vivo functional perturbation modeling combined with single-cell RNA sequencing is transforming how immune dysfunction is defined, and ultimately how it is therapeutically targeted. In this workshop, Graph Therapeutics will share data demonstrating this in action: by pairing high-content screening with whole transcriptome profiling at single-cell resolution across large patient and donor cohorts, they map disease-relevant immune states to drive systematic dysfunction mapping and accelerate precision target discovery.
