Immunometabolism in Autoimmunity

Moderator(s)

• SG

  Stefania Gallucci

  Univ Massachusetts Chan Medical School
• LM

  Laurence Morel

  University of Texas Health Science Center, San Antonio

Presentations:

• 3:45 PM - 4:00 PM US ET

  T Cell-Specific Deletion of Glutaminase (Gls1) Lowers AutoAb Production in Lupus Mice by Altering Metabolism and Function of Follicular Helper T Cells
  

  Author: Milind Joshi (he/him/his) – UT Hlth. San Antonio
• 4:00 PM - 4:15 PM US ET

  De novo pyrimidine synthesis controls lupus-prone germinal center B cell and plasma cell fates
  

  Author: Julia Weber – Thomas Jefferson University
• 4:15 PM - 4:30 PM US ET

  Itaconate alleviates autoimmune uveitis by boosting FOXP3 and blocking succinate-driven inflammation
  

  Author: Sukhvinder Singh, PhD (he/him/his) – Wayne State University School of Medicine
• 4:45 PM - 5:00 PM US ET

  Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation
  

  Author: Hongxu Xian, PhD – Versiti Blood Res. Inst.