Neurodegenerative & Autoimmune Disorders

Moderator(s)

• 

  Rafael Rezende, PhD (he/him/his)

  Assistant Professor of Neurology
  Harvard Med. Sch.
  Natick, Massachusetts, United States
• 

  Uma Sriram, PHD

  Associate Professor
  Temple Univ. Katz Sch. of Med., United States

Presentations:

• 8:00 AM - 8:15 AM US ET

  Engineered probiotics limit T-cell driven CNS autoimmunity by activating AHR-KLF4-FADS3 signaling in intestinal dendritic cells
  

  Author: Carolina M. Polonio, PhD – Brigham and Women’s Hosp, Harvard Med. Sch.
• 8:15 AM - 8:30 AM US ET

  Aging-Associated Nrf2 Loss in Microglia Exacerbates Neuroinflammation and Trained Immunity
  

  Author: Jui-Hung Jimmy Yen, PhD (he/him/his) – Indiana University School of Medicine
• 8:30 AM - 8:45 AM US ET

  CD40+ MHC-II+ astrocytes promote Th17 cell-driven CNS autoimmunity
  

  Author: Joon-Hyuk Lee, PhD (he/him/his) – Harvard Medical School
• 8:45 AM - 9:00 AM US ET

  Gamma-Delta T cell–microglia crosstalk drives CD8⁺ T cell infiltration and promotes Alzheimer’s-like pathology in APP/PS1 mice
  

  Author: Rafael Rezende, PhD (he/him/his) – Harvard Med. Sch.
• 9:00 AM - 9:15 AM US ET

  Repeated brain resident memory T cell reactivation induces microglial and T cell remodeling and sustained microglia activation in Alzheimer’s disease
  

  Author: Tiffany Chen (she/her/hers) – Dartmouth College
• 9:15 AM - 9:30 AM US ET

  Meningeal lymphoid hubs support autoreactive immune responses
  

  Author: Nagela Ghabdan Zanluqui, PhD (she/her/hers) – National Institutes of Health