Inflammatory Mechanisms in Systemic Autoimmunity

Moderator(s)

• KN

  Kerstin Nundel, PhD (she/her/hers)

  Assistant Professor
  UMass Chan Med. Sch.
  Worcester, Massachusetts, United States
• TL

  Tobias Lanz

  Assistant Professor
  Institute for Immunity, Transplantation, and Infection (ITI)
  Stanford Univ. Sch. of Med.
  Stanford, California, United States

Presentations:

• 12:45 PM - 1:00 PM US ET

  Antigen-driven MAIT cell activation restores skin Treg levels and attenuates lupus-like skin inflammation
  

  Author: Grace Crossland – Dartmouth College
• 1:00 PM - 1:15 PM US ET

  IRF1 tunes the IRF4–IRF8 axis to drive effector B-cell fates in autoimmunity and inflammaging
  

  Author: Eddie-Williams Owiredu – Univ. of Alabama, Birmingham
• 1:15 PM - 1:30 PM US ET

  Role of B cell activation through Toll-like receptors in Systemic Lupus Erythematosus.
  

  Author: Rodrigo Cervantes, PhD (he/him/his) – Boston Children's Hospital
• 1:30 PM - 1:45 PM US ET

  GM-CSF-IRF5 Axis as a Therapeutic Target in TLR7-Mediated Macrophage Activation Syndrome
  

  Author: Ailing Lu, PhD – Feinstein Institutes for Medical Research, Northwell Health
• 1:45 PM - 2:00 PM US ET

  E3 Ubiquitin Ligase Peli1 Regulates TLR7-Driven Spontaneous Germinal Center and Plasma Cell Development
  

  Author: Tien Bui (she/her/hers) – Thomas Jefferson University
• 2:00 PM - 2:15 PM US ET

  TLR7/9–IFNα–LDHB Checkpoint Rewires NET Subtypes in Lupus
  

  Author: Andrew Monteith, PhD – University of Tennessee-Knoxville