Major Symposium F: 20 Years of Th17 Cells: Discovery and Clinical Impact

Saturday, April 18, 2026

8:00 AM - 11:15 AM US ET

Location: Ballroom

Chair(s)

Sarah Gaffen, PhD (she/her/hers)

Professor
Univ. of Pittsburgh, United States
Vijay Kuchroo, DVM, PhD

Director
Gene Lay Inst. of Immunol. and Inflammation
Chestnut Hill, Massachusetts, United States

Vijay Kuchroo, DVM, PhD

Director
Gene Lay Inst. of Immunol. and Inflammation
Chestnut Hill, Massachusetts, United States
DC

Daniel Cua

VP, Distinguished Fellow
Johnson & Johnson, USA
Shreya Das, Shreya Das PhD

Research Associate
Albany Med. Col., United States
Sarah Gaffen, PhD (she/her/hers)

Professor
Univ. of Pittsburgh, United States
Jun Huh, PhD

Associate Professor
Harvard Med. Sch., United States
Dan Littman, MD, PhD (he/him/his)

Professor
HHMI, NYU Sch. of Med.
New York, New York, United States
MM

Mandy McGeachy, PhD

professor
Cornell Univ., United States
Alice Taliento, PhD

Postdoctoral Fellow
Massachusetts Gen. Hosp., United States

Disclosure(s):

Sarah L. Gaffen, PhD: No relevant disclosure to display

Vijay K. Kuchroo, DVM, PhD: No financial relationships to disclose

Shreya Das, Shreya Das PhD: No financial relationships to disclose

Jun R. Huh, PhD: No relevant disclosure to display

Dan R. Littman, MD, PhD: No financial relationships to disclose

Mandy J. McGeachy, PhD: No financial relationships to disclose

Alice Emma Taliento, PhD: No financial relationships to disclose

8:00 AM - 8:10 AM US ET

Introduction
Speaker: Vijay K. Kuchroo, DVM, PhD – Gene Lay Inst. of Immunol. and Inflammation
8:10 AM - 8:41 AM US ET

IL-23 regulation of Th17 immune pathway in autoimmune inflammation
Speaker: Daniel Cua – Johnson & Johnson
8:41 AM - 9:12 AM US ET

Th17 influencers
Speaker: Mandy J. McGeachy – Cornell Univ.
9:12 AM - 9:43 AM US ET

The immune cellular network defined by RORyt
Speaker: Dan R. Littman, MD, PhD (he/him/his) – HHMI, NYU Sch. of Med.
9:43 AM - 9:58 AM US ET

Dietary Iron Overload Rewires Regulatory T Cells into IL-17–Mediated Proinflammatory Effectors Aggravating Yersinia enterocolitica Infection
Author: Shreya Das, Shreya Das PhD – Albany Med. Col.
9:58 AM - 10:29 AM US ET

At the crossroads of IL-17 signaling: IL-17 signal transduction in autoimmunity and fungal infections
Speaker: Sarah L. Gaffen, PhD (she/her/hers) – Univ. of Pittsburgh
10:29 AM - 10:44 AM US ET

A unique subset of allergen specific T helper 2+17 tissue resident memory cells is established in a mouse model of allergic inflammation
Author: Alice Emma Taliento, PhD – Massachusetts Gen. Hosp.
10:44 AM - 11:15 AM US ET

Unexpected roles of interleukin‑17 and identification of its target cells
Speaker: Jun R. Huh, PhD – Harvard Med. Sch.