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Thursday, Apr 16th
9:45 AM - 10:00 AM
US ET
Antibody-Drug Conjugates (ADCs) as Adaptors for Universal CAR T cells
Location: 157
Author:
Elisa Ruffo, PhD (she/her/hers)
– Univ. of Pittsburgh Sch. of Med.
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
10:00 AM - 10:15 AM
US ET
Decoding Histone-DNA Methylation Crosstalk in Exhausted T Cells to Enhance Immunotherapy
Location: 157
Author:
Hazem E. Ghoneim, PhD
– Ohio State Univ. Col. of Med.
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
10:15 AM - 10:30 AM
US ET
mRNA Vaccines Enhance Tumor Control and Synergize with 4-1BB Costimulatory Therapy
Location: 157
Author:
Tanushree Dangi, PhD (she/her/hers)
– Beth Israel Deaconess Medical Center, Harvard Medical School
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
10:30 AM - 10:45 AM
US ET
In situ Transglutaminase 2-mediated Crosslinking of Engineered IL-7 to the Tumor Matrix Enhances Immunotherapy and Anti-PD-1 Response
Location: 157
Author:
Angie Chun, PhD (she/her/hers)
– New York University
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
10:45 AM - 11:00 AM
US ET
Intratumoral administration of a single dose of the HEPLISAV-B Vaccine and IL-15 complexes induces tumor regression in Triple Negative Brest Cancer
Location: 157
Author:
Malia E. Leifheit, MS, BS (she/her/hers)
– Rush Univ.
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
11:00 AM - 11:15 AM
US ET
Prime-Target neoantigen vaccination strategy enhances neoantigen-specific T cell immunity at the tumor microenvironment in murine cold tumor models
Location: 157
Author:
Kou Hioki, PhD (he/him/his)
– Erasmus University Medical Center
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
4:15 PM - 4:30 PM
US ET
Oncolytic HSV-1 Encoding IL-12 and Anti-PD-1 Reprograms CNS Immunity: Open-Label Study of MVR-C5252 for Safety, Tolerability, and Efficacy (PuMP)
Location: 205
Author:
Elizabeth Owens, B.S. (she/her/hers)
– Duke Univ. Sch. of Med.
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
4:30 PM - 4:45 PM
US ET
Opposing Effects of Metoclopramide and Bromocriptine on Melanoma Response to Immune Checkpoint Blockade
Location: 205
Author:
Mark Gregory, MS
– Karmanos Cancer Inst., Wayne State Univ.
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
4:45 PM - 5:00 PM
US ET
Myoglobin expression boosts T-cell metabolism and antitumor effector function
Location: 205
Author:
Julia Werner, M.Sc. (she/her/hers)
– Heinrich Heine University Düsseldorf
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
5:00 PM - 5:15 PM
US ET
Skin mites enhance virtual memory T cell responses against immune checkpoint inhibitor-resistant tumors
Location: 205
Author:
Jihoon Oh, PhD (he/him/his)
– National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
5:15 PM - 5:30 PM
US ET
Targeting glycans for cancer immunotherapy
Location: 205
Author:
Jessica Stark, PhD (she/her/hers)
– Massachusetts Institute of Technology
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Thursday, Apr 16th
5:30 PM - 5:45 PM
US ET
Leveraging extrafollicular B cells for the treatment of solid tumors
Location: 205
Author:
Allison Casey, BS
– University of Pittsburgh
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
12:45 PM - 1:00 PM
US ET
Extracellular cAMP as a potent immune modulator promotes T cell exhaustion in chronic lymphocytic leukemia
Location: 205
Author:
Shokrollah Elahi, MD, PhD (he/him/his)
– University of Alberta
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
1:00 PM - 1:15 PM
US ET
Identification of a FoxP3-specific small molecule degrader with potent antitumor immunotherapeutic efficacy
Location: 205
Author:
Amy Tang
– Northwestern University
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
1:15 PM - 1:30 PM
US ET
Immunological targeting of the endogenous retroviral protein ERVMER34-1 in carcinomas promotes epitope spread and enhances response to PD-L1 blockade
Location: 205
Author:
Duane H. Hamilton, PhD (he/him/his)
– National Cancer Institute, Center for Cancer Research, National Institutes of Health
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
1:30 PM - 1:45 PM
US ET
A universal CD4 epitope enhances cytotoxic T-cell priming and memory in glioblastoma peptide vaccination
Location: 205
Author:
Kelly Hotchkiss, PhD
– Duke University School of Medicine
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
1:45 PM - 2:00 PM
US ET
Mouse EL4 lymphoma strains differentially respond to a loss of BCATc from T cells and αCTLA4 immunotherapy
Location: 205
Author:
Elitsa Ananieva-Stoyanova, PhD (she/her/hers)
– Des Moines University
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)
Saturday, Apr 18th
2:00 PM - 2:15 PM
US ET
The role of the transcription factor Blimp-1 in T cells in anti-PD1 immunotherapy in non-small cell lung cancer
Location: 205
Author:
Susetta Finotto, PhD (she/her/hers)
– University Hospital Erlangen
Tumor Immunology: Checkpoints, Prevention, And Treatment (TIPT)