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  • Wednesday, Apr 15th
    2:45 PM - 3:00 PM US ET
    Glucocorticoid signaling shapes the differentiation of tumor-infiltrating CD8+ T cells through TXNIP-dependent metabolic rewiring
    Location: 156
    Author: Dandan Yang, PhD (she/her/hers) – Brigham and Women's Hospital, Harvard Medical School
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Wednesday, Apr 15th
    3:00 PM - 3:15 PM US ET
    CD4+ T cell-mediated Immune Surveillance during Intestinal Tumor Initiation
    Location: 156
    Author: Kelly McGovern (she/her/hers) – Harvard Univ.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Wednesday, Apr 15th
    3:15 PM - 3:30 PM US ET
    DUSP4 regulates anti-tumor CD8+ T cell response in colorectal cancer
    Location: 156
    Author: Yongliang Zhang, PhD (he/him/his) – Yong Loo Lin School of Medicine, NUS
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Wednesday, Apr 15th
    3:30 PM - 3:45 PM US ET
    Spatial colocalization of neoantigen-expressing tumor cells and cognate T cells in cancer
    Location: 156
    Author: Adi Nagler, PhD (she/her/hers) – Dana-Farber/Harvard Cancer Center
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Wednesday, Apr 15th
    3:45 PM - 4:00 PM US ET
    TCR-Associated Rasal1 rewires T-cell mitochondrial metabolism to regulate checkpoint immunotherapy
    Location: 156
    Author: Nikhil Ponnoor Anto, PhD (he/him/his) – Univ. de Montreal
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    8:00 AM - 8:15 AM US ET
    The BMP-KLF3 circuit promotes resilient programming in CD8+ T cells during chronic infection and cancer
    Location: 157
    Author: Abbey Saadey (she/her/hers) – Ohio State University
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    8:15 AM - 8:30 AM US ET
    HuR–SerpinB9 Axis Regulates Tumor T-Cell Fitness and Persistence via Post-Transcriptional Control
    Location: 157
    Author: Paramita Chakraborty (she/her/hers) – Medical University of South Carolina
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    8:45 AM - 9:00 AM US ET
    Spatial IgA Plasma Cell Niches Drive Anti-Tumor Immunity in Pancreatic Cancer
    Location: 157
    Author: Lily Liu (she/her/hers) – Augusta University
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    9:00 AM - 9:15 AM US ET
    CAR-T with ICOS costimulation lacks therapeutic efficacy in patients due to strong trogocytosis and failure of expansion
    Location: 157
    Author: Yongxia Wu, MD, PhD (she/her/hers) – Medical College of Wisconsin
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    9:15 AM - 9:30 AM US ET
    Burn Baby Burn: Leveraging Fatty Acid Oxidation to Improve CD8+ T cell Efficacy Against Ovarian Cancer.
    Location: 157
    Author: Emily-Claire K. Duffy (she/her/hers) – Dartmouth College
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Thursday, Apr 16th
    3:30 PM - 4:30 PM US ET
    TIME3 - Spatial and metabolic guidance on tailoring anti-tumor immunity
    Location: 153C
    Speaker: Ping-Chih Ho, PhD (he/him/his) – Univ. of Lausanne
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Friday, Apr 17th
    4:15 PM - 4:30 PM US ET
    Targeting genome organizer Satb1 in regulatory T cells safely and potently enhances cancer immunity
    Location: 153AB
    Author: Ephraim A. Ansa-Addo, PhD (he/him/his) – The Ohio State University
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Friday, Apr 17th
    4:30 PM - 4:45 PM US ET
    Cancer-associated metabolites stimulate mucosal-associated invariant T cells for cancer cell killing.
    Location: 153AB
    Author: Ariel R. Laub (she/her/hers) – University of Texas at San Antonio
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Friday, Apr 17th
    4:45 PM - 5:00 PM US ET
    Psoriasis-like disease prevents squamous skin tumour development by neutrophil-driven inflammation
    Location: 153AB
    Author: Panagiota Tsokkou – Vienna Gen. Hosp.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Friday, Apr 17th
    5:00 PM - 5:15 PM US ET
    Antigen Presentation by Tumor Endothelium Promotes CD8+ T Cell Recruitment
    Location: 153AB
    Author: Yoojung Kwon, PhD (she/her/hers) – Washington Univ. Sch. of Med., St. Louis
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Friday, Apr 17th
    5:15 PM - 5:30 PM US ET
    Transcriptional and post-translational regulation of B7-H4
    Location: 153AB
    Author: Jiali Yu – University of Michigan
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    8:00 AM - 8:15 AM US ET
    Deletion of RIAM in myeloid cells accelerates tumor growth by macrophage reprogramming
    Location: 156
    Author: Anthos Christofides, MD, PhD – The University of Texas MD Anderson Cancer Center
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    8:15 AM - 8:30 AM US ET
    Olfactory receptor 2+ tumor-associated macrophages activate CD8+ T cells to suppress tumor growth
    Location: 156
    Author: Elayne Benson – Med. Col. of Georgia, Augusta Univ.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    8:30 AM - 8:45 AM US ET
    MARCKS Drives Immunosuppressive Signaling in Tumor-Associated Macrophages to Promote Lung Cancer Progression
    Location: 156
    Author: Jenna M. Berton (she/her/hers) – Univ. of California, Davis
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    8:45 AM - 9:00 AM US ET
    Respiratory viral infections prime accelerated lung cancer growth
    Location: 156
    Author: Wei Qian, PhD – University of Virginia
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    9:00 AM - 9:15 AM US ET
    GARP+ Erythroid Regulatory Cells (G-ERCs) define spatially organized immunosuppressive niches that restrain anti-tumor immunity
    Location: 156
    Author: Maria Velegraki, MD, PhD – Ohio State Univ.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    9:00 AM - 9:15 AM US ET
    GARP+ Erythroid Regulatory Cells (G-ERCs) define spatially organized immunosuppressive niches that restrain anti-tumor immunity
    Location: 156
    Author: Maria Velegraki, MD, PhD – Ohio State Univ.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    9:45 AM - 10:00 AM US ET
    T cell adaption to bile acids is critical for their responses during liver tumors.
    Location: 156
    Author: Siva Karthik Varanasi – UMass Chan Med. Sch.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    10:00 AM - 10:15 AM US ET
    GSDME-Mediated Pyroptosis Suppresses Anti-Tumor Immunity via IL-1α–Dependent Recruitment of Immunosuppressive Myeloid Cells
    Location: 156
    Author: Yu Mei – Natl. Univ. of Singapore
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    10:15 AM - 10:30 AM US ET
    Targeting Pros1 to improve chemotherapy efficacy and immune anti-tumor response
    Location: 156
    Author: Nestor Prieto-Dominguez, PhD (he/him/his) – University of Kentucky
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Saturday, Apr 18th
    10:30 AM - 10:45 AM US ET
    Exocyst complex regulates fungal-mediated IL-33 release and facilitates type 2 immune response
    Location: 156
    Author: Aftab Alam, PhD (he/him/his) – Roswell Park Comprehensive Cancer Center
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    8:00 AM - 8:15 AM US ET
    Type I Interferon priming in Macrophages is associated with poor responses in Patients with Advanced Prostate Cancer
    Location: 156
    Author: David E. Sanin, PhD (he/him/his) – Johns Hopkins Univ. Sch. of Med.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    8:15 AM - 8:30 AM US ET
    T6B-mediated inhibition of the miRISC decreases myeloid-derived suppressor cell abundance and enhances survival in a murine ovarian cancer model
    Location: 156
    Author: Joshua Imperatore, PhD (he/him/his) – Magee-Womens Res. Inst. & Fndn.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    8:30 AM - 8:45 AM US ET
    AXL tyrosine kinase inhibition restores anti-PD-1 efficacy in melanoma through tumor-associated macrophage–dependent mechanisms
    Location: 156
    Author: Amanda Kirane – Stanford University
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    8:45 AM - 9:00 AM US ET
    Loss of the Y chromosome evokes extrinsic extramedullary myelopoiesis via genome-wide epigenetic reprogramming of bladder cancer tumor cells
    Location: 156
    Author: Jay Mandula, PhD, BS (he/him/his) – Ohio State University
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    9:00 AM - 9:15 AM US ET
    Immune organ tertiary lymphoid structures (TLSs) as a therapeutic strategy for solid tumors
    Location: 156
    Author: Sudip Paudel, PhD – Wyss Institute
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    9:45 AM - 10:00 AM US ET
    Defining the Stress–Gut Microbiome Interplay in Anti-Tumor B Cell Response
    Location: 156
    Author: Hilal Bashir, Doctorate (he/him/his) – Weill Cornell Medicine
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    10:00 AM - 10:15 AM US ET
    B cells facilitate immune evasion of metastasizing cancer cells in tumor-draining lymph nodes
    Location: 156
    Author: Alice Bertocchi, PhD (she/her/hers) – Dana-Farber Cancer Inst.
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    10:15 AM - 10:30 AM US ET
    Overcoming tumor-intrinsic immunotherapy resistance with hypofractionated radiotherapy
    Location: 156
    Author: Lewis Z. Shi, MD, PhD (he/him/his) – University of Alabama, Birmingham
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    10:30 AM - 10:45 AM US ET
    Spatio-temporal mapping of immune cell dynamics during human sequential lymph node metastasis
    Location: 156
    Author: Qiuchen Zhao, PhD (he/him/his) – University of Cambridge
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    10:45 AM - 11:00 AM US ET
    A Cross-Species Nerve- and Airway-Associated Macrophage Program that Drives Lung Tumor Progression and Immunotherapy Resistance
    Location: 156
    Author: Kamal Khanna
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)
  • Sunday, Apr 19th
    11:00 AM - 11:15 AM US ET
    Role of EHF in regulating B cell checkpoint molecule TIM-1 and development of CD11c⁺TIM-1⁺ Age-associated B cells
    Location: 156
    Author: Yoon Chul Kye – Brigham and Women's Hospital, Harvard Medical School
    Tumor Immunology: Cellular Responses and Tumor Microenvironment (TIME)