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Thursday, Apr 16th
9:45 AM - 10:00 AM
US ET
Understanding unconventional T cell development to generate an ‘off the shelf’ immunotherapy to treat human diseases
Location: 156
Author:
Daniel Pellicci, PhD
– Murdoch Children's Research Institute
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
9:45 AM - 11:15 AM
US ET
TI2 - Understanding immune responses to optimize immune intervention
Location: 156
Moderator:
Eduardo Davila
– University of Colorado, Denver
Moderator:
Juliet Williams
– Kymera Therapeutics
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
10:00 AM - 10:15 AM
US ET
Single-cell buoyant mass reveals CD8⁺ T-cell fitness and predicts melanoma checkpoint response
Location: 156
Author:
JIAQUAN YU, PhD
– Koch Inst. for Integrative Cancer Res., MIT
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
10:15 AM - 10:30 AM
US ET
Single Cell Insights on Inflammation-Induced Transitional States in Benign Prostate Hyperplasia
Location: 156
Author:
Nikhila T. Suresh, PhD (she/her/hers)
– Florida Atlantic University
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
10:30 AM - 10:45 AM
US ET
Optimizing Cancer Antibody Effectiveness: Pharmacology and Mathematical Modeling to Achieve Better Clinical Outcomes
Location: 156
Author:
Denise Faustman, MD, PhD
– Massachusetts General Hospital/Harvard Medical School
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
10:45 AM - 11:00 AM
US ET
Morning influenza vaccination elicits superior antigen-specific immune responses in adults aged 60-85 years
Location: 156
Author:
Tamara Brouwers, MSc (she/her/hers)
– Dutch National Institute for Public Health and the Environment
Translational and Interventional Immunology (TI)
Thursday, Apr 16th
11:00 AM - 11:15 AM
US ET
BCG vaccine induces distinct metabolic shifts in monocytes in vitro and peripheral blood plasma in vivo: Implications for neonatal trained immunity
Location: 156
Author:
Asimenia Angelidou, MD, PhD (she/her/hers)
– Boston Children's Hosp., Harvard Med. Sch.
Translational and Interventional Immunology (TI)
Friday, Apr 17th
12:45 PM - 1:00 PM
US ET
Preliminary immunologic and clinical Phase 1b study outcomes from patients with ROSAH syndrome treated with the first-in-class ALPK1 inhibitor DF-003
Location: 205
Speaker:
Neil Solomons, MB BS
– Drug Farm
Translational and Interventional Immunology (TI)
Friday, Apr 17th
12:45 PM - 2:15 PM
US ET
TI4 - Interrogation of chronic immunity and interventional approaches
Location: 205
Moderator:
Daniela Cipolletta, PhD
– Seismic Therapeutic
Moderator:
Gerald Morris
– University of California, San Diego
Translational and Interventional Immunology (TI)
Friday, Apr 17th
1:00 PM - 1:15 PM
US ET
Host HLA Allelic Variation Shapes Risk of Severe SARS-CoV-2 Infection and Long COVID
Location: 205
Author:
Grace Kim, MS, PhD
– Louisiana State University Health, New Orleans
Translational and Interventional Immunology (TI)
Friday, Apr 17th
1:15 PM - 1:30 PM
US ET
Discovery of potent, selective and insurmountable MRGPRX2 antagonists for mast cell-driven disorders
Location: 205
Author:
Yves Millet, PhD
– Blueprint Medicines Corporation
Translational and Interventional Immunology (TI)
Friday, Apr 17th
1:30 PM - 1:45 PM
US ET
Engineered Nanobodies for Durable Tolerance in Allergic Asthma
Location: 205
Author:
Floris J. van Dalen, PhD
– Boston Children's Hosp., Harvard Med. Sch.
Translational and Interventional Immunology (TI)
Friday, Apr 17th
1:45 PM - 2:00 PM
US ET
Persistent IL-17 Cytokine Patterns and Th17 Expansion Characterize Chronic Critical Illness after Severe Trauma
Location: 205
Author:
Caleb Y. Kim, BS
– University of Minnesota, Twin Cities
Translational and Interventional Immunology (TI)
Friday, Apr 17th
2:00 PM - 2:15 PM
US ET
Targeting the Adenosine–Adenosine Deaminase-1 Axis to Restore HIV-Specific CD8⁺ T Cell Function
Location: 205
Author:
Arden O. Edgerton (she/her/hers)
– Drexel University College of Medicine
Translational and Interventional Immunology (TI)
Saturday, Apr 18th
12:45 PM - 1:45 PM
US ET
TI7 - Adaptive T cell immunity in infection, vaccination, and neurodegeneration
Location: 157
Speaker:
Allessandro Sette
– La Jolla Inst. for Immunol
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
8:00 AM - 8:33 AM
US ET
From signal to strategy: Integrating biomarkers in clinical trials to accelerate drug development in transplant
Location: 253
Speaker:
Donna Flesher, PhD (she/her/hers)
– Biogen
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
8:00 AM - 8:33 AM
US ET
From signal to strategy: Integrating biomarkers in clinical trials to accelerate drug development in transplant
Location: 253
Speaker:
Donna Flesher, PhD (she/her/hers)
– Biogen
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
8:33 AM - 9:06 AM
US ET
Generative design of antibody Fc variants with synthetic and programmable immune function
Location: 253
Speaker:
Sai Reddy
– ETH Zurich
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
9:06 AM - 9:21 AM
US ET
Intranasal administration of a pan-reactive influenza antibody reveals Fc-independent mode of protection
Location: 253
Author:
Faez Amokrane Nait Mohamed, PhD (he/him/his)
– Harvard Medical School
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
9:21 AM - 9:54 AM
US ET
Engineering cytokine/antibody fusion proteins as targeted immunotherapeutics
Location: 253
Speaker:
Jamie Spangler
– Johns Hopkins Univ.
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
9:21 AM - 9:54 AM
US ET
Engineering cytokine/antibody fusion proteins as targeted immunotherapeutics
Location: 253
Speaker:
Jamie Spangler
– Johns Hopkins Univ.
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
9:54 AM - 10:09 AM
US ET
Targeted immunosuppression with a tissue-selective PD-1 agonist prevents rejection of transplanted hearts
Location: 253
Author:
James A. Torchia, MD, PhD
– Dana-Farber Cancer Institute, Harvard Medical School
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
10:09 AM - 10:42 AM
US ET
Vitiligo treatment from the Bronze Age to the Age of Biologics: New hope for an ancient disease
Location: 253
Speaker:
John E. Harris
– Mass Gen. Brigham
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
10:09 AM - 10:42 AM
US ET
Vitiligo treatment from the Bronze Age to the Age of Biologics: New hope for an ancient disease
Location: 253
Speaker:
John E. Harris
– Mass Gen. Brigham
Translational and Interventional Immunology (TI)
Sunday, Apr 19th
10:42 AM - 11:15 AM
US ET
Decoding adaptive immunity
Location: 253
Speaker:
Michael Birnbaum, PhD
– MIT
Translational and Interventional Immunology (TI)