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  • Thursday, Apr 16th
    8:00 AM - 8:15 AM US ET
    Metabolic checkpoint AhR prevents pathogenic B cell expansion in murine lupus
    Location: 156
    Author: John D. Mountz, PhD MD – Univ. of Alabama, Birmingham
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    8:15 AM - 8:30 AM US ET
    SP2H selectively depletes Stimulator of Interferon Genes (STING), reducing inflammation and improving survival in Trex1-/- mice
    Location: 156
    Author: Richard Bethell, DPhil (he/him/his) – Sulis Therapeutics
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    8:30 AM - 8:45 AM US ET
    Reduced BCMA Signaling Disrupts the BAFF/APRIL Axis and Promotes Inflammatory Cytokine Production by B Cells in Multiple Sclerosis.
    Location: 156
    Author: Gaurav Kumar, PhD (he/him/his) – Oklahoma Med. Res. Fndn.
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    8:45 AM - 9:00 AM US ET
    The antigen-specific immunotherapy, AKS-107, selectively depletes anti-insulin B lymphocytes in the pancreas and reduces insulitis in T1D-prone mice
    Location: 156
    Author: Tyler W. Jenkins, PhD – Vanderbilt Univ. Med. Ctr.
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    9:00 AM - 9:15 AM US ET
    Functional dichotomy of GC-Derived Memory B Cells in Lupus: A Role for FCRL5+ MBCs in ASC Differentiation
    Location: 156
    Author: Ajitanuj Rattan, PhD (he/him/his) – Boston Children's Hosp., Harvard Med. Sch.
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    9:15 AM - 9:30 AM US ET
    A Six-month Ketogenic Diet Alters The Immune And Metabolic Landscape In Multiple Sclerosis
    Location: 156
    Author: Wesley Godfrey – Johns Hopkins Univ. Sch. of Med.
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    12:45 PM - 1:00 PM US ET
    Site-Selective Proximity-Synthetic Editors Rewrite p53 Acetylation to Dynamically Control Treg Lineage Differentiation
    Location: 253
    Author: Francisco F. Gonzalez, PhD (he/him/his) – Icahn School of Medicine, Mount Sinai
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    1:00 PM - 1:15 PM US ET
    GNTI-932: A Targeted, Scalable, and Hypoimmune Allogeneic Engineered Treg therapy for the treatment of Inflammatory Bowel Disease.
    Location: 253
    Author: Martina Sassone-Corsi, PhD – GentiBio
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    1:15 PM - 1:30 PM US ET
    Engineered Nanobodies to Direct and Visualize Durable Tolerance
    Location: 253
    Author: Novalia Pishesha, PhD – Boston Children's Hosp., Harvard Med. Sch.
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    1:30 PM - 1:45 PM US ET
    First Oral Small-molecule Inhibitors Designed by Generative AI Achieve Biologics-Like Pan-Inhibition of IL-17AA, AF, and FF Dimers
    Location: 253
    Author: Chris Li, PhD – ByteDance AI Drug Discovery / Anew Therapeutics
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    1:45 PM - 2:00 PM US ET
    Antigen-specific depletion of gluten-reactive T cells for the potential treatment of celiac disease
    Location: 253
    Author: Kaitlin A. Read, PhD – University of Pennsylvania
    Therapeutic Approaches to Autoimmunity (THER)
  • Thursday, Apr 16th
    2:00 PM - 2:15 PM US ET
    UVB Phototherapy Induces a Stress-Driven Anergy Pathway as a Novel Axis of T Cell Regulation
    Location: 253
    Author: Avishai maliah, MD PHD – Tel Aviv Univ. Sackler Fac. of Med.
    Therapeutic Approaches to Autoimmunity (THER)