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  • Thursday, Apr 16th
    3:45 PM - 3:57 PM US ET
    A Novel Mediator Extracellular Caspase-1 Worsens Acute Lung Injury in Sepsis
    Location: 156
    Author: Kohei Ishikawa, MD, PhD (he/him/his) – The Feinstein Institutes for Medical Research
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    3:57 PM - 4:09 PM US ET
    Investigating the role of Dectin-1 in the host immune responses to Schistosoma mansoni cercariae in acute schistosomiasis
    Location: 156
    Author: Megan Nitchman – The Pennsylvania State University
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    4:09 PM - 4:21 PM US ET
    MARCO is an IFN-restricted immunometabolic decoy LPS receptor
    Location: 156
    Author: Shriram Ramani – UMass Chan Med. Sch.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    4:21 PM - 4:33 PM US ET
    Structural and biological bases of cGAS bending bubble DNA to form a hyperactive dimer
    Location: 156
    Author: Shuangshuang Yang, PhD – The University of North Carolina at Chapel Hill
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    4:33 PM - 4:45 PM US ET
    Guanylate-Binding Protein 5 (GBP5) Exacerbates Sepsis by Inhibiting STING-mediated Post-Golgi Transport
    Location: 156
    Author: Yiyu Yang – BenQ Hospital
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    4:45 PM - 4:57 PM US ET
    Microbiome-Derived RNA as a Trigger for Heritable Innate Immunity
    Location: 156
    Author: Vladimir Lazetic, PhD DVM – George Washington Univ.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Thursday, Apr 16th
    4:57 PM - 5:09 PM US ET
    TRIM21 Orchestrates Inflammasome Assembly and Drives Autoinflammatory Pathology.
    Location: 156
    Author: Jessica Carriere, PhD – Cedars-Sinai Medical Center
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:00 AM - 8:15 AM US ET
    ATF3 Regulates Cholesterol Trafficking in Macrophages
    Location: 156
    Author: Amelia M. Pearson (she/her/hers) – Univ. of Cincinnati Col. of Med.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:15 AM - 8:30 AM US ET
    Host Lipid and Mitochondrial Metabolism Networks as Functional Targets for Novel Antimicrobials against Intracellular Bacteria
    Location: 156
    Author: Catharine Bosio, PhD (she/her/hers) – National Institute of Allergy and Infectious Diseases, National Institutes of Health
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:30 AM - 8:45 AM US ET
    Homologous MHC Antigens Induce cDC1-like Differentiation from Monocyte-Derived Dendritic Cells
    Location: 156
    Author: Sharon Bright Amanya, MS – Baylor Col. of Med.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:45 AM - 9:00 AM US ET
    Regulation of Inflammatory Diseases by Solute Carrier Transporters
    Location: 156
    Author: Ravi Bharadwaj, PhD – UMass Chan Med. Sch.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    9:00 AM - 9:15 AM US ET
    The bacterial quorum-sensing molecule 2′-aminoacetophenone reprograms macrophage metabolism and sustains histone lactylation for persistence.
    Location: 156
    Author: Arijit Chakraborty, MS-PhD (he/him/his) – Massachusetts Gen. Hosp., Harvard Med. Sch.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    9:15 AM - 9:30 AM US ET
    UVRAG and the VPS34 complex II regulate macropinocytosis via the synthesis of PI(3)P on the plasma membrane
    Location: 156
    Author: Astha Neupane (she/her/hers) – South Dakota State Univ.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:00 AM - 11:15 AM US ET
    INM3 - Major Symposium C: Epigenetic Modifiers as Drivers of Immune Function
    Location: 253
    Chair: Maziar Divangahi – McGill Univ.
    Chair: Anjana Rao – La Jolla Inst. for Immunol.
    Speaker: Maziar Divangahi – McGill Univ.
    Speaker: Luis Barreiro – Univ. of Chicago
    Speaker: Gargi Mishra, PHD – University of Washington
    Speaker: Patrick G. Hogan, PhD – La Jolla Inst. for Immunol. and Moores Cancer Ctr. at UCSD
    Speaker: Junji Zhu, PhD – Florida Research and Innovation Center, Cleveland Clinic
    Speaker: Edward Chuong – Univ. of Colorado, Boulder
    Speaker: Aki Minoda, PhD – Radboud Univ.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    8:33 AM - 9:06 AM US ET
    Epigenetic regulation of innate immune responses
    Location: 253
    Speaker: Luis Barreiro – Univ. of Chicago
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    9:21 AM - 9:54 AM US ET
    Early chromatin and transcriptional changes driven by NFAT and its transcriptional partners in 'exhausted' CD8+ T cells
    Location: 253
    Speaker: Patrick G. Hogan, PhD – La Jolla Inst. for Immunol. and Moores Cancer Ctr. at UCSD
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    9:54 AM - 10:09 AM US ET
    Reversible ISG15 conjugation regulates antiviral innate immunity and intracellular metabolism
    Location: 253
    Author: Junji Zhu, PhD – Florida Research and Innovation Center, Cleveland Clinic
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    10:09 AM - 10:42 AM US ET
    Transposon control of immune gene regulatory networks
    Location: 253
    Speaker: Edward Chuong – Univ. of Colorado, Boulder
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)
  • Friday, Apr 17th
    10:42 AM - 11:15 AM US ET
    Sterile inflammation is a key feature of intrinsic tissue ageing
    Location: 253
    Speaker: Aki Minoda, PhD – Radboud Univ.
    Innate Immune Responses and Host Defense: Molecular Mechanisms (INM)