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Thursday, Apr 16th
9:45 AM - 10:00 AM US ET
KDM5C-regulated anabolic metabolism is required for T cell expansion
Location: 153AB
Author: Connie Krawczyk, PhD – Van Andel Inst.
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
10:00 AM - 10:15 AM US ET
A distal transcribed enhancer of KRAS fine-tunes Tfh-mediated vaccine response
Location: 153AB
Author: Dhaneshwar Kumar (he/him/his) – National Institutes of Health
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
10:15 AM - 10:30 AM US ET
Copper Shapes T Cell Metabolism and Epigenetics to Drive Pathogenic Th17 Cell Function in Autoimmunity
Location: 153AB
Author: Lucile Noyer, PhD (she/her/hers) – NYU Grossman Sch. of Med.
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
10:30 AM - 10:45 AM US ET
Translational control of T cell expansion and autoimmune responses by a non-conventional RNA binding protein
Location: 153AB
Author: Shachi Vyas, PhD (she/her/hers) – University of Pittsburgh
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
10:45 AM - 11:00 AM US ET
Exportin-5 Links miRNA Biogenesis to the Preservation of B Cell Receptor Surface Expression
Location: 153AB
Author: Tylar Kirch (he/him/his) – University of Vermont
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
4:15 PM - 4:30 PM US ET
Heterogeneity in the Naïve CD8⁺ T Pool Shapes the Infection Response
Location: 157
Author: Connor Kean – Cornell University
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
4:30 PM - 4:45 PM US ET
A BACH2-STAT5 transcriptional module licenses a short intracellular C3 proteoform in activated CD4+ T cells
Location: 157
Author: Jorge Trujillo – National Institutes of Health
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
4:45 PM - 5:00 PM US ET
KLF2 regulates CD8 T cell differentiation and migration in infection and cancer
Location: 157
Author: Tuoqi Wu, PhD (he/him/his) – Univ. of Texas Southwestern Med. Ctr.
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
5:00 PM - 5:15 PM US ET
RORα governs CD8⁺ T cell memory subset specification and offers a therapeutic node for antiviral immunity
Location: 157
Author: Jonathan Chuck, M.S (he/him/his) – Scripps Res. Skaggs Grad. Sch. of Chem. and Bio. Sci.
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
5:15 PM - 5:30 PM US ET
RNF144A enforces IL-2-STAT5 dominance over RAF-ERK-MAPK signaling in antiviral CD8 T cells
Location: 157
Author: Dhaneshwar Kumar (he/him/his) – National Institutes of Health
Immune Response Regulation: Molecular Mechanisms (IRM)
Thursday, Apr 16th
4:45 PM - 5:45 PM US ET
IRM3 - Mechanisms of restraint: From immune homeostasis to immunoresilience
Location: 153C
Speaker: Carla V. Rothlin – Univ. of Minnesota, Twin Cities
Immune Response Regulation: Molecular Mechanisms (IRM)
Friday, Apr 17th
8:00 AM - 8:30 AM US ET
IRM5 - Discovery and targeting of human B cell epitopes to counter emerging threats
Location: 102
Speaker: Camila H. Coelho, PhD MBA – Icahn School of Medicine at Mount Sinai
Immune Response Regulation: Molecular Mechanisms (IRM)
Friday, Apr 17th
8:30 AM - 9:00 AM US ET
IRM5 - Harnessing host glutamine metabolism for host-directed tuberculosis therapy
Location: 102
Speaker: Sadiya Parveen-Nesson (she/her/hers) – Louisiana State Univ. Hlth., Shreveport
Immune Response Regulation: Molecular Mechanisms (IRM)
Friday, Apr 17th
9:00 AM - 9:30 AM US ET
IRM5 - Scalable platforms to study and engineer immune receptors
Location: 102
Speaker: Brandon J. Dekosky – Ragon Inst. of MGH, MIT, and Harvard
Immune Response Regulation: Molecular Mechanisms (IRM)
Friday, Apr 17th
9:06 AM - 9:21 AM US ET
Epigenetic and lineage-specific transcription factors regulate the cell type specific induction of type I and type III interferons
Location: 253
Author: Gargi Mishra, PHD – University of Washington
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
9:45 AM - 10:00 AM US ET
Glucose Uptake by Germinal Center B Cells Selectively Sustains Autoimmunity While Sparing Responses to Foreign Antigens
Location: 151
Author: Urmi Hofland (she/her/hers) – UT Hlth. San Antonio
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
10:00 AM - 10:15 AM US ET
Uncovering a role of aryl hydrocarbon receptor (AhR) in the differentiation dynamics of human B cells
Location: 151
Author: Luis J. Mena Hernandez, MD, MS – Univ. of Pittsburgh Sch. of Med.
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
10:15 AM - 10:30 AM US ET
Cell cycle-coupled transcriptional network regulates human B cell fate bifurcation
Location: 151
Author: Nick Pease, PhD – University of Pittsburgh
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
10:30 AM - 10:45 AM US ET
Aging disrupts the affinity threshold for naïve B cell germinal center participation
Location: 151
Author: Braxton Greer (he/him/his) – National Institute on Aging, National Institutes of Health
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
10:45 AM - 11:00 AM US ET
SLC7A5-mediated glutamine export is required for humoral immunity
Location: 151
Author: Ruifeng Sun, MPhil (he/him/his) – Yale University
Immune Response Regulation: Molecular Mechanisms (IRM)
Sunday, Apr 19th
11:00 AM - 11:15 AM US ET
Dynamic nutrient sensing in plasma cells licenses immunoglobulin A secretion
Location: 151
Author: Simona Ceglia, PhD (she/her/hers) – UNIVERSITY OF MASSACHUSETTS
Immune Response Regulation: Molecular Mechanisms (IRM)